| Research | Pre-Clinical | Phase 1 | Phase 2 | Phase 3 | |
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Solid Tumors, IV administration, USA |
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Solid Tumors, Oral administration, RUS |
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Hematological Malignancies |
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Novel DNA intercalating anticancer drug curaxin CBL0137 significantly inhibited in vitro DNA methylation by eukaryotic DNA methyltransferase Dnmt3a catalytic domain…
Thus, we propose a novel role for FACT as a factor preventing helicase dissociation from chromatin during replication stress. View…
Two posters with the results of completed clinical trials that described CBL0137 safety, pharmacokinetics, and efficacy in patients with advanced…
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